Objective: This study evaluated the antianxiety effect of Citrus aurantium aroma (neroli oil) inhalation on patients with acute coronary syndrome (ACS).
Design: A double-blind, placebo-controlled randomized trial.
Setting/Location: This study was conducted in the Coronary Care Unit of Torfeh Hospital in Tehran, Iran, from September 2017 to February 2018.
Subjects: A total of 140 hospitalized ACS patients (mean age = 56.72 ± 11.38 years)
Interventions: Eligible patients were randomly assigned to citrus aroma and placebo groups to receive inhalation aromatherapy 2 days after hospitalization. Citrus aroma was 30% essential oil of Citrus aurantiumL. flowers in paraffin, which was administrated three times a day. The placebo group received paraffin similarly.
Outcome measures: The rate of anxiety was measured at baseline and after intervention using the State–Trait Anxiety Inventory.
Results: At baseline, citrus aroma and placebo groups were similar in demographic characteristics as well as anxiety scores. After intervention, mean anxiety scores in the two groups become significantly different; the scores were 34.66 ± 9.6 and 42.36 ± 6.4 for citrus aroma and placebo groups, respectively (p< 0.0001). No side effect was observed.
Conclusions: According to the current findings, aromatherapy with Citrus aurantium L. aroma (neroli oil) may be a safe and efficient intervention and can be considered an easy and applicable method to reduce anxiety in patients with ACS.
Citrus aurantium Aroma for Anxiety in Patients with Acute Coronary Syndrome: A Double-Blind Placebo-Controlled Trial | The Journal of Alternative and Complementary Medicine
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